Anti-CDK1 Polyclonal Antibody
| 英文名称 | Anti-CDK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDC2;CDC28A;P34CDC2 |
| 应用 | WB IHC IF IP |
| 稀释比例 | WB 1:200-1000. IHC 1:50-100. IF 1:50-100. IP 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 34kDa |
| Gene ID | 983 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CDK1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CDK1 |
| Subcellular Locations | Cytoplasm Mitochondrion Nucleus centrosome cytoskeleton microtubule organizing center spindle |
| Swiss Prot | P06493 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |