Anti-CYP2E1 Polyclonal Antibody
| 英文名称 | Anti-CYP2E1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CPE1;CYP2E;P450-J;P450C2E |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 57kDa |
| Gene ID | 1571 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CYP2E1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CYP2E1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P05181 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. |