Anti-PLAUR Polyclonal Antibody
| 英文名称 | Anti-PLAUR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD87;UPAR;URKR;U-PAR |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 37kDa |
| Gene ID | 5329 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PLAUR |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PLAUR |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q03405 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |