Anti-PLK3 Polyclonal Antibody
品牌：solarbio | 货号：K005954P
| 英文名称 | Anti-PLK3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CNK;FNK;PLK-3;PRK |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 72kDa |
| Gene ID | 1263 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PLK3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PLK3 |
| Subcellular Locations | Cytoplasm Golgi apparatus Nucleus centrosome cytoskeleton microtubule organizing center nucleolus |
| Swiss Prot | Q9H4B4 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. |