Anti-GDNF Polyclonal Antibody
品牌：solarbio | 货号：K008157P
| 英文名称 | Anti-GDNF Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ATF1;ATF2;HSCR3;HFB1-GDNF |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 24kDa |
| Gene ID | 14573 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GDNF |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GDNF |
| Swiss Prot | P48540 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. |