Anti-PRSS2 Polyclonal Antibody
品牌:solarbio | 货号:K005557P
英文名称 |
Anti-PRSS2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
TRY2;TRY8;TRYP2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
26kDa |
Gene ID |
5645 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PRSS2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PRSS2 |
Subcellular Locations |
Secreted extracellular space |
Swiss Prot |
P07478 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants. |