Anti-CDH16 Polyclonal Antibody
品牌：solarbio | 货号：K005527P
| 英文名称 | Anti-CDH16 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDH16 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 90kDa |
| Gene ID | 1014 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CDH16 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CDH16 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | O75309 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. |