Anti-SKIL Polyclonal Antibody
品牌：solarbio | 货号：K007186P
| 英文名称 | Anti-SKIL Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SNO;SnoA;SnoI;SnoN |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 77kDa |
| Gene ID | 6498 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SKIL |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SKIL |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P12757 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |