Anti-TNNI3 Polyclonal Antibody
品牌:solarbio | 货号:K004924P
英文名称 |
Anti-TNNI3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CMD1FF;CMD2A;CMH7;RCM1;TNNC1;cTnI |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
24kDa |
Gene ID |
7137 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TNNI3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TNNI3 |
Subcellular Locations |
Cytoskeleton Cytosol |
Swiss Prot |
P19429 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |