Anti-CD206 Polyclonal Antibody
品牌:solarbio | 货号:K006619P
英文名称 |
Anti-CD206 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CLEC13D;Macrophage mannose receptor 1;Mannose receptor;mannose receptor;C type 1;MMR;MRC1 |
应用 |
WB IHC FC |
稀释比例 |
WB 1:500-1000. IHC 1:200-800. |
蛋白分子量 |
170kDa |
Gene ID |
4360 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CD206 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CD206 |
Subcellular Locations |
Cell membrane Endosome Membrane |
Swiss Prot |
P22897 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
CD206 is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane glycoprotein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains, a transmembrane domain, and an intracellular carboxy-terminal tail. |