Anti-FasLG Polyclonal Antibody
品牌：solarbio | 货号：K001613P
| 英文名称 | Anti-FasLG Polyclonal Antibody |
|---|---|
| 应用2 | WB |
| 宿主 | Rabbit |
| 别名 | ALPS1B;APT1LG1;APTL;CD178;CD95-L;CD95L;FASL;TNFSF6;TNLG1A |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 蛋白分子量 | 31kDa |
| Gene ID | 356 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human FasLG |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human FasLG |
| Subcellular Locations | Cell membrane Cytoplasmic vesicle lumen Lysosome lumen Nucleus Secreted Single-pass type II membrane protein |
| Swiss Prot | P48023 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. |