Anti-Bcl-2 Monoclonal Antibody
品牌：solarbio | 货号：K200018M
| 英文名称 | Anti-Bcl-2 Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | Apoptosis regulator Bcl 2;Bcl 2;B cell leukemia/lymphoma 2 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:1000-2000. IHC 1:100-300. IF 1:100-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 26kDa |
| Gene ID | 596 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Mitochondrion outer membrane Nucleus membrane Endoplasmic reticulum membrane |
| Swiss Prot | P10415 |
| 克隆号 | 6B5 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. |