Anti-CASP3 Polyclonal Antibody
品牌:solarbio | 货号:K101291P
英文名称 |
Anti-CASP3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CPP32;CPP32B;SCA-1;SREBP cleavage activity 1;Cysteine protease CPP32 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:80. |
交叉反应 |
Human Mouse |
蛋白分子量 |
31kDa |
Gene ID |
836 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CASP3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CASP3 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P42574 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-|-Gly-217’ bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |