Anti-PCNA Monoclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PCNA Monoclonal Antibody

品牌:solarbio | 货号:K200030M

英文名称 Anti-PCNA Monoclonal Antibody
宿主 Mouse
别名 Proliferating Cell Nuclear Antigen;DNA polymerase delta auxiliary protein;PCNAR
应用 WB IHC
稀释比例 WB 1:10000-15000. IHC 1:100-300.
蛋白分子量 29kDa
Gene ID 5111
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 A synthetic peptide coupled to KLH
性状 液体
Public Immunogen Range A synthetic peptide coupled to KLH
Subcellular Locations Nucleus
Swiss Prot P12004
克隆号 12D10
克隆类型 Monoclonal Antibody
背景资料 PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.