Anti-LILRB4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-LILRB4 Polyclonal Antibody

品牌:solarbio | 货号:K004989P

英文名称 Anti-LILRB4 Polyclonal Antibody
宿主 Rabbit
别名 CD85K;ILT-3;ILT3;LIR-5;LIR5
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 49kDa
Gene ID 11006
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human LILRB4
性状 液体
Public Immunogen Range Recombinant protein of human LILRB4
Subcellular Locations Cell membrane Single-pass type I membrane protein
Swiss Prot Q8NHJ6
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.