Anti-LILRB4 Polyclonal Antibody
品牌：solarbio | 货号：K004989P
| 英文名称 | Anti-LILRB4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD85K;ILT-3;ILT3;LIR-5;LIR5 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 49kDa |
| Gene ID | 11006 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human LILRB4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human LILRB4 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | Q8NHJ6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |