Anti-Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Polyclonal Antibody

品牌:solarbio | 货号:K006217P

英文名称 Anti-Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Polyclonal Antibody
宿主 Rabbit
别名 ERK;p38;p40;p41;ERK2;ERT1;MAPK2;PRKM1;PRKM2;P42MAPK;p41mapk;
应用 WB IP
稀释比例 WB 1:500-2000. IP 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 41kDa
Gene ID 5594/5595
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding T202 of human ERK1
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding T202 of human ERK1
Subcellular Locations Cytoskeleton Nucleus
Swiss Prot P28482; P27361
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.