Anti-Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Polyclonal Antibody
品牌:solarbio | 货号:K006217P
英文名称 |
Anti-Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ERK;p38;p40;p41;ERK2;ERT1;MAPK2;PRKM1;PRKM2;P42MAPK;p41mapk; |
应用 |
WB IP |
稀释比例 |
WB 1:500-2000. IP 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
41kDa |
Gene ID |
5594/5595 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A phospho specific peptide corresponding to residues surrounding T202 of human ERK1 |
性状 |
液体 |
Public Immunogen Range |
A phospho specific peptide corresponding to residues surrounding T202 of human ERK1 |
Subcellular Locations |
Cytoskeleton Nucleus |
Swiss Prot |
P28482; P27361 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |