Anti-IL2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IL2 Polyclonal Antibody

品牌:solarbio | 货号:K106549P

英文名称 Anti-IL2 Polyclonal Antibody
宿主 Rabbit
别名 IL-2;lymphokine;TCGF;Interleukin-2;T-cell growth factor
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 18kDa
Gene ID 3558
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human IL2
性状 液体
Public Immunogen Range A synthetic peptide of human IL2
Subcellular Locations Secreted
Swiss Prot P60568
克隆类型 Polyclonal Antibody
背景资料 Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.