Anti-PPP2R1B Polyclonal Antibody
品牌:solarbio | 货号:K004726P
| 英文名称 | Anti-PPP2R1B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PP2A-Abeta;PR65B |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 66kDa |
| Gene ID | 5519 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PPP2R1B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PPP2R1B |
| Subcellular Locations | secreted |
| Swiss Prot | P30154 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. |