Anti-KRT18 Polyclonal Antibody
品牌：solarbio | 货号：K106590P
| 英文名称 | Anti-KRT18 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CK-18;CYK18;K18;PIG46;Cytokeratin-18 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 26kDa |
| Gene ID | 3875 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KRT18 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KRT18 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P05783 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |