Anti-β Catenin Monoclonal Antibody
品牌：solarbio | 货号：K200022M
| 英文名称 | Anti-β Catenin Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | CTNNB;Cadherin associated protein;b-catenin |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 92kDa |
| Gene ID | 1499 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P35222 |
| 克隆号 | 13C6 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. |