Anti-TLR4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TLR4 Polyclonal Antibody

品牌:solarbio | 货号:K106584P

英文名称 Anti-TLR4 Polyclonal Antibody
宿主 Rabbit
别名 ARMD10;CD284;TLR-4;TOLL
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 73kDa
Gene ID 7099
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human TLR4
性状 液体
Public Immunogen Range Recombinant protein of human TLR4
Subcellular Locations Cytoplasm Cell membrane
Swiss Prot O00206
克隆类型 Polyclonal Antibody
背景资料 Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.