Anti-TLR4 Polyclonal Antibody
品牌:solarbio | 货号:K106584P
英文名称 |
Anti-TLR4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ARMD10;CD284;TLR-4;TOLL |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
73kDa |
Gene ID |
7099 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TLR4 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TLR4 |
Subcellular Locations |
Cytoplasm Cell membrane |
Swiss Prot |
O00206 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. |