Anti-TIMP1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TIMP1 Polyclonal Antibody

品牌:solarbio | 货号:K101524P

英文名称 Anti-TIMP1 Polyclonal Antibody
宿主 Rabbit
别名 ABH;ABH1;ALKBH;alkB;hABH
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human
蛋白分子量 33kDa
Gene ID 7076
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TIMP1
性状 液体
Public Immunogen Range A synthetic peptide of human TIMP1
Subcellular Locations Secreted
Swiss Prot P01033
克隆类型 Polyclonal Antibody
背景资料 Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.