Anti-CASP8 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CASP8 Polyclonal Antibody

品牌:solarbio | 货号:K106679P

英文名称 Anti-CASP8 Polyclonal Antibody
宿主 Rabbit
别名 ALPS2B;CAP4;Casp-8;FLICE;MACH;MCH5
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 55kDa
Gene ID 841
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CASP8
性状 液体
Public Immunogen Range A synthetic peptide of human CASP8
Subcellular Locations Cytoplasm
Swiss Prot Q14790
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli.