Anti-CASP8 Polyclonal Antibody
品牌:solarbio | 货号:K106679P
英文名称 |
Anti-CASP8 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ALPS2B;CAP4;Casp-8;FLICE;MACH;MCH5 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
55kDa |
Gene ID |
841 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CASP8 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CASP8 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q14790 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. |