Anti-APEX1 Polyclonal Antibody
品牌：solarbio | 货号：K008099P
| 英文名称 | Anti-APEX1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APE;APX;APE1;APEN;APEX;HAP1;REF1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:15-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 36kDa |
| Gene ID | 328 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human APEX1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human APEX1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P27695 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. |