Anti-PCNA Polyclonal Antibody
品牌:solarbio | 货号:K000323P
英文名称 |
Anti-PCNA Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ATLD2 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
蛋白分子量 |
29kDa |
Gene ID |
5111 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PCNA |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PCNA |
Subcellular Locations |
Nucleus |
Swiss Prot |
P12004 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |