Anti-CD45 Monoclonal Antibody
品牌:solarbio | 货号:K200020M
英文名称 |
Anti-CD45 Monoclonal Antibody |
宿主 |
Mouse |
别名 |
GP180;L CA;CD45 antigen |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-3000. IHC 1:100-300. |
交叉反应 |
Human |
蛋白分子量 |
147kDa |
Gene ID |
5788 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG1 |
免疫原 |
A synthetic peptide coupled to KLH |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide coupled to KLH |
Subcellular Locations |
Membrane Membrane raft |
Swiss Prot |
P08575 |
克隆号 |
12A9 |
克隆类型 |
Monoclonal Antibody |
背景资料 |
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45. |