Anti-HDAC8 Polyclonal Antibody
品牌:solarbio | 货号:K004238P
| 英文名称 | Anti-HDAC8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDA07;CDLS5;HD8;HDACL1;MRXS6;RPD3;WTS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 42kDa |
| Gene ID | 55869 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HDAC8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HDAC8 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9BY41 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |