Anti-CYP46 Polyclonal Antibody
品牌:solarbio | 货号:K107031P
英文名称 |
Anti-CYP46 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CYP46A1;CP46;CYP46;cholesterol 24-hydroxylase |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
蛋白分子量 |
57/46/38kDa |
Gene ID |
10858 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CYP46 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CYP46 |
Subcellular Locations |
Nucleus Cytoplasm Cell membrane |
Swiss Prot |
Q9Y6A2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. |