Anti-DNM1L Polyclonal Antibody
品牌：solarbio | 货号：K003440P
| 英文名称 | Anti-DNM1L Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DLP1;DRP1;DVLP;DYMPLE;EMPF;EMPF1;HDYNIV |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 82kDa |
| Gene ID | 10059 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DNM1L |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DNM1L |
| Subcellular Locations | Cytoplasm Cytoplasmic vesicle Endomembrane system Golgi apparatus Membrane Mitochondrion outer membrane Peripheral membrane protein Peroxisome clathrin-coated pit cytosol secretory vesicle synaptic vesicle membrane |
| Swiss Prot | O00429 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer’s disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |