Anti-TLR4 Polyclonal Antibody
品牌：solarbio | 货号：K003881P
| 英文名称 | Anti-TLR4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARMD10;CD284;TLR-4;TOLL |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 96kDa |
| Gene ID | 7099 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TLR4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TLR4 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | O00206 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. |