Anti-HS71A Polyclonal Antibody
品牌:solarbio | 货号:K101528P
英文名称 |
Anti-HS71A Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ABL;JTK7;bcr/abl;c-ABL;c-ABL1;p150;v-abl |
应用 |
WB |
稀释比例 |
WB 1:2500. |
交叉反应 |
Human |
蛋白分子量 |
70kDa |
Gene ID |
3303/3304. |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human HS71A |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human HS71A |
Subcellular Locations |
Cytoskeleton Nucleus |
Swiss Prot |
P0DMV8 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. |