Anti-ASPSCR1 Polyclonal Antibody
品牌:solarbio | 货号:K005278P
| 英文名称 | Anti-ASPSCR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ASPCR1;ASPL;ASPS;RCC17;TUG;UBXD9;UBXN9 |
| 应用 | WB IHC IF IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 60kDa |
| Gene ID | 79058 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ASPSCR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ASPSCR1 |
| Subcellular Locations | Cytoplasm Endomembrane system Endoplasmic reticulum-Golgi intermediate compartment membrane Nucleus Peripheral membrane protein |
| Swiss Prot | Q9BZE9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. |