Anti-ASPSCR1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ASPSCR1 Polyclonal Antibody

品牌:solarbio | 货号:K005278P

英文名称 Anti-ASPSCR1 Polyclonal Antibody
宿主 Rabbit
别名 ASPCR1;ASPL;ASPS;RCC17;TUG;UBXD9;UBXN9
应用 WB IHC IF IP
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 60kDa
Gene ID 79058
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ASPSCR1
性状 液体
Public Immunogen Range Recombinant protein of human ASPSCR1
Subcellular Locations Cytoplasm Endomembrane system Endoplasmic reticulum-Golgi intermediate compartment membrane Nucleus Peripheral membrane protein
Swiss Prot Q9BZE9
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.