Anti-YBX-1 Polyclonal Antibody
品牌:solarbio | 货号:K107045P
英文名称 |
Anti-YBX-1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BP-8,CBF-A,CSDA2,CSDB,DBPB,EFI-A,MDR-NF1,NSEP-1,NSEP1,YB-1,YB1,Y-box binding protein 1 |
应用 |
WB IHC |
稀释比例 |
WB 1:5000-8000. IHC 1:50-200. |
蛋白分子量 |
36kDa |
Gene ID |
4904 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human YBX-1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human YBX-1 |
Subcellular Locations |
Nucleus Cytoplasm Secreted?? |
Swiss Prot |
P67809 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. |