Anti-DSC2 Polyclonal Antibody
品牌：solarbio | 货号：K107040P
| 英文名称 | Anti-DSC2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARVD11,CDHF2,DG2,DGII/III,DSC3,desmocollin-2 |
| 应用 | WB |
| 稀释比例 | WB 1:8000-12000. |
| 蛋白分子量 | 100/94kDa |
| Gene ID | 1824 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human DSC2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human DSC2 |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | Q02487 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. |