Anti-DSC2 Polyclonal Antibody
品牌:solarbio | 货号:K107040P
英文名称 |
Anti-DSC2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ARVD11,CDHF2,DG2,DGII/III,DSC3,desmocollin-2 |
应用 |
WB |
稀释比例 |
WB 1:8000-12000. |
蛋白分子量 |
100/94kDa |
Gene ID |
1824 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human DSC2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human DSC2 |
Subcellular Locations |
Cytoplasm Cell membrane |
Swiss Prot |
Q02487 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. |