Anti-DSC2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-DSC2 Polyclonal Antibody

品牌:solarbio | 货号:K107040P

英文名称 Anti-DSC2 Polyclonal Antibody
宿主 Rabbit
别名 ARVD11,CDHF2,DG2,DGII/III,DSC3,desmocollin-2
应用 WB
稀释比例 WB 1:8000-12000.
蛋白分子量 100/94kDa
Gene ID 1824
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human DSC2
性状 液体
Public Immunogen Range A synthetic peptide of human DSC2
Subcellular Locations Cytoplasm Cell membrane
Swiss Prot Q02487
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.