Anti-S100B Monoclonal Antibody
品牌：solarbio | 货号：K000002M
| 英文名称 | Anti-S100B Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | NEF;S100;S100-B;S100beta |
| 应用 | WB |
| 稀释比例 | WB 1:500. |
| 交叉反应 | Rat |
| 蛋白分子量 | 10kDa |
| Gene ID | 6285 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | lgG2b |
| 免疫原 | Human S100B synthetic peptide conjugated to KLH. |
| 性状 | 液体 |
| Public Immunogen Range | Human S100B synthetic peptide conjugated to KLH. |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P04271 |
| 克隆号 | 5G3-C11 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer’s disease, Down’s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]. |