Anti-Phospho-MAX-S11 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-MAX-S11 Polyclonal Antibody

品牌:solarbio | 货号:K006195P

英文名称 Anti-Phospho-MAX-S11 Polyclonal Antibody
宿主 Rabbit
别名 bHLHd4
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-200.
交叉反应 Human
蛋白分子量 18kDa
Gene ID 4149
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding S11 of human MAX
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding S11 of human MAX
Subcellular Locations Cell projection Nucleus dendrite
Swiss Prot P61244
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.