Anti-Phospho-MAX-S11 Polyclonal Antibody
品牌:solarbio | 货号:K006195P
英文名称 |
Anti-Phospho-MAX-S11 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
bHLHd4 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
18kDa |
Gene ID |
4149 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A phospho specific peptide corresponding to residues surrounding S11 of human MAX |
性状 |
液体 |
Public Immunogen Range |
A phospho specific peptide corresponding to residues surrounding S11 of human MAX |
Subcellular Locations |
Cell projection Nucleus dendrite |
Swiss Prot |
P61244 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. |