Anti-CARD11 Polyclonal Antibody
品牌：solarbio | 货号：K005045P
| 英文名称 | Anti-CARD11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BENTA;BIMP3;CARMA1;IMD11;PPBL |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 133kDa |
| Gene ID | 84433 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CARD11 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CARD11 |
| Subcellular Locations | Cytoplasm Membrane raft |
| Swiss Prot | Q9BXL7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. |