Anti-SIRT3 Polyclonal Antibody
品牌：solarbio | 货号：K005158P
| 英文名称 | Anti-SIRT3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SIR2L3 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:100-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 44kDa |
| Gene ID | 23410 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SIRT3 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SIRT3 |
| Subcellular Locations | Mitochondrion matrix |
| Swiss Prot | Q9NTG7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. |