Anti-SIRT3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SIRT3 Polyclonal Antibody

品牌:solarbio | 货号:K005158P

英文名称 Anti-SIRT3 Polyclonal Antibody
宿主 Rabbit
别名 SIR2L3
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:100-200.
交叉反应 Human Mouse Rat
蛋白分子量 44kDa
Gene ID 23410
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human SIRT3
性状 液体
Public Immunogen Range A synthetic peptide of human SIRT3
Subcellular Locations Mitochondrion matrix
Swiss Prot Q9NTG7
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.