Anti-COQ3 Polyclonal Antibody
品牌：solarbio | 货号：K005270P
| 英文名称 | Anti-COQ3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DHHBMT;DHHBMTASE;UG0215E05;bA9819.1 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 41kDa |
| Gene ID | 51805 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COQ3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COQ3 |
| Subcellular Locations | Matrix side Mitochondrion inner membrane Peripheral membrane protein |
| Swiss Prot | Q9NZJ6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol. |