Anti-IL7 Polyclonal Antibody
品牌：solarbio | 货号：K008039P
| 英文名称 | Anti-IL7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL-7 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 20kDa |
| Gene ID | 3574 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL7 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL7 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P13232 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. |