Anti-ALDH3A1 Polyclonal Antibody
品牌:solarbio | 货号:K004041P
| 英文名称 | Anti-ALDH3A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALDH3;ALDHIII |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 50kDa |
| Gene ID | 218 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ALDH3A1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ALDH3A1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P30838 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. |