Anti-FOXO1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-FOXO1 Polyclonal Antibody

品牌:solarbio | 货号:K007489P

英文名称 Anti-FOXO1 Polyclonal Antibody
宿主 Rabbit
别名 FKH1;FKHR;FOXO1A
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 70kDa
Gene ID 2308
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human FOXO1
性状 液体
Public Immunogen Range A synthetic peptide of human FOXO1
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q12778
克隆类型 Polyclonal Antibody
背景资料 This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import.