Anti-FOXO1 Polyclonal Antibody
品牌:solarbio | 货号:K007489P
英文名称 |
Anti-FOXO1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
FKH1;FKHR;FOXO1A |
应用 |
IHC |
稀释比例 |
IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
70kDa |
Gene ID |
2308 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human FOXO1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human FOXO1 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q12778 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import. |