Anti-PCDHA13 Polyclonal Antibody
品牌：solarbio | 货号：K005275P
| 英文名称 | Anti-PCDHA13 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CNR5;CNRN5;CNRS5;CRNR5;PCDH-ALPHA13 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Mouse Rat |
| 蛋白分子量 | 102kDa |
| Gene ID | 56136 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PCDHA13 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PCDHA13 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | Q9Y5I0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. |