Anti-TRF1 Polyclonal Antibody
品牌：solarbio | 货号：K107057P
| 英文名称 | Anti-TRF1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Telomeric repeat-binding factor;1PIN2;TRBF1;TRF;TRF1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 50/48kDa |
| Gene ID | 7013 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TRF1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TRF1 |
| Subcellular Locations | Nucleus Cytoplasm? |
| Swiss Prot | P54274 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Binds the telomeric double-stranded 5′-TTAGGG-3′ repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5′-TTAGGG-3′ repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. |