Anti-TRF1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TRF1 Polyclonal Antibody

品牌:solarbio | 货号:K107057P

英文名称 Anti-TRF1 Polyclonal Antibody
宿主 Rabbit
别名 Telomeric repeat-binding factor;1PIN2;TRBF1;TRF;TRF1
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human
蛋白分子量 50/48kDa
Gene ID 7013
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TRF1
性状 液体
Public Immunogen Range A synthetic peptide of human TRF1
Subcellular Locations Nucleus Cytoplasm?
Swiss Prot P54274
克隆类型 Polyclonal Antibody
背景资料 Binds the telomeric double-stranded 5′-TTAGGG-3′ repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5′-TTAGGG-3′ repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.