Anti-C8B Polyclonal Antibody
品牌：solarbio | 货号：K005758P
| 英文名称 | Anti-C8B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | C82 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 67kDa |
| Gene ID | 732 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human C8B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human C8B |
| Subcellular Locations | Secreted |
| Swiss Prot | P07358 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. |