Anti-ATP6V1B1 Polyclonal Antibody
品牌：solarbio | 货号：K004835P
| 英文名称 | Anti-ATP6V1B1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ATP6B1;RTA1B;VATB;VMA2;VPP3 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 57kDa |
| Gene ID | 525 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ATP6V1B1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ATP6V1B1 |
| Subcellular Locations | Endomembrane system Peripheral membrane protein |
| Swiss Prot | P15313 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c’, c”, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. |