Anti-HYAL1 Polyclonal Antibody
品牌:solarbio | 货号:K004664P
英文名称 |
Anti-HYAL1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HYAL-1;LUCA1;MPS9;NAT6 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
48kDa |
Gene ID |
3373 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human HYAL1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human HYAL1 |
Subcellular Locations |
Lysosome Secreted |
Swiss Prot |
Q12794 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. |