Anti-CNTN1 Polyclonal Antibody
品牌：solarbio | 货号：K107050P
| 英文名称 | Anti-CNTN1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Contactin-1,Glycoprotein gp135 |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 蛋白分子量 | 113/71kDa |
| Gene ID | 1272 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CNTN1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CNTN1 |
| Subcellular Locations | Cell membrane Extracellular matrix Cytoplasm? |
| Swiss Prot | Q12860 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth. |