Anti-ACE Polyclonal Antibody
品牌:solarbio | 货号:K106540P
英文名称 |
Anti-ACE Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACE1;CD143;DCP;DCP1;ACE1;CD143;DCP;DCP1;ICH;MVCD3 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
120kDa |
Gene ID |
1636 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ACE |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ACE |
Subcellular Locations |
Cell membrane Cytoplasm Secreted Single-pass type I membrane protein |
Swiss Prot |
P12821 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. |