Anti-SURF1 Polyclonal Antibody
品牌:solarbio | 货号:K004773P
英文名称 |
Anti-SURF1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CMT4K |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
33kDa |
Gene ID |
6834 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SURF1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SURF1 |
Subcellular Locations |
Mitochondrion inner membrane Multi-pass membrane protein |
Swiss Prot |
Q15526 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. |