Anti-SURF1 Polyclonal Antibody
品牌:solarbio | 货号:K004773P
| 英文名称 | Anti-SURF1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CMT4K |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 33kDa |
| Gene ID | 6834 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SURF1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SURF1 |
| Subcellular Locations | Mitochondrion inner membrane Multi-pass membrane protein |
| Swiss Prot | Q15526 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. |